This is a long form exploration of thyroid hormone replacement in the absence of a thyroid gland. Spanning decades of dosing structures and cultural shifts in thyroid care, this project draws from lived experience, laboratory data, medical records, and journals. It examines regulatory loss, tissue response, sufficiency, and buffering through the lens of a patient without endogenous thyroid function.
It reads best in order on Substack but can be picked up at any place in the history. Start here: https://substack.com/home/post/p-189286111

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